Ozone therapy is gaining attention in integrative medicine as a therapy that may support circulation, immune balance and cellular energy production. Used by some functional and integrative physicians—including practitioners serving North Texas patients—it is part of a growing focus on therapies that work with the body’s regulatory systems rather than targeting isolated symptoms.

Medical ozone therapy uses controlled ozone gas as a mild oxidative stimulus. The body responds by strengthening antioxidant defenses, improving oxygen utilization and supporting mitochondrial activity, which plays a central role in energy production.

“Ozone therapy is a useful tool in functional medicine because it works at the level of cellular energy,” says Shelley Cole, M.D., an integrative physician and educator. “When the body can produce energy efficiently, many systems function better.”

Practitioners may incorporate ozone therapy into broader care plans that also include nutrition therapy, gut health support, detoxification strategies and lifestyle interventions. In clinical settings, it has been explored for wound care, chronic infections, circulatory support and inflammatory conditions when used appropriately and under trained supervision.

Digestive health is often addressed first. Poor nutrient absorption can contribute to fatigue, immune imbalance and inflammation. Some integrative practitioners use ozone therapy alongside dietary and microbiome strategies to help restore balance.

Oral health is another area of collaboration. Biological dentists may use ozone in dental procedures to reduce infection risk and support healing, particularly when addressing hidden infections or preparing for dental surgery.

Because ozone therapy involves medical procedures, appropriate training and screening are essential. Individuals considering ozone therapy should consult qualified healthcare professionals to determine whether it is appropriate for their condition and to understand potential risks and benefits.

The American Academy of Ozone Therapy Annual Meeting will be held May 7–9 at the Omni Las Colinas Hotel in Dallas. The conference brings together physicians, dentists and researchers to discuss training standards, safety protocols and emerging clinical applications.

Integrative therapies such as ozone therapy are not stand-alone cures but can be part of comprehensive care that includes nutrition, movement, sleep support and medical guidance. With individualized treatment plans, many patients find improvements in resilience, energy and recovery.

Dr. Shelley Cole is an integrative physician with more than 30 years in practice and Mayo Clinic training in Obstetrics & Gynecology. For information about ozone therapy services, call 254-343-7837 or visit AAOT.US for conference details.